Top Supplements to Lower Cortisol, Manage Stress & Boost Energy in 2025
Discover the most effective supplements to reduce cortisol, manage stress, and reclaim your energy with natural adaptogens and proven ingredients.
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Do you wake up tired, feel on edge by lunch, and crash by dinner? Millions struggle with these telltale signs of elevated cortisol.
This powerful stress hormone serves a vital purpose, helping your body respond to immediate threats by releasing energy and sharpening focus. But when cortisol remains chronically high due to ongoing stress, it wreaks havoc on your sleep, weight, mood, and overall health.
You don't have to accept this exhausting cycle as your new normal. Natural cortisol reducers, particularly evidence-based supplements like adaptogens for cortisol regulation, are a good place to start.
From ashwagandha's stress-busting properties to magnesium's calming effects, the right cortisol-lowering supplements can help restore your body's natural rhythm and reclaim your energy. Here are the most effective supplements to reduce cortisol and help you feel like yourself again;
Key Takeaways
- Ashwagandha, magnesium, and omega-3s are proven to regulate cortisol, calm stress, and improve energy.
- Consistent use for 2-4 weeks brings the best results.
- Pair supplements with daily habits for lasting relief.
What is Cortisol? Symptoms and Solutions
Cortisol, often called the ‘stress hormone’, is produced by your adrenal glands and plays a vital role in your body’s response to stress (Ref). It helps regulate energy by releasing glucose, supports your immune system, and manages inflammation (Ref).
In short bursts, cortisol is essential for survival, enabling your body to handle immediate challenges. However, when cortisol levels remain elevated due to chronic stress, it can lead to serious health issues.
Prolonged high cortisol levels are linked to anxiety, weight gain, poor sleep, and fatigue. This happens because the hormone disrupts your metabolism, weakens your immune system, and interferes with your sleep-wake cycle.
Over time, these effects can significantly impact your physical and mental well-being.
The good news is that lifestyle changes and natural cortisol reducers, such as adaptogens like ashwagandha and supplements for anxiety and stress, can help normalize cortisol levels. Incorporating the best supplements to reduce cortisol into your routine, alongside stress management techniques, can restore balance and improve your overall health.
Dr. Mark Hyman, Functional Medicine Expert, says that “Cortisol management is crucial for overall well-being. Adaptogens like ashwagandha have been shown to effectively reduce stress and balance cortisol levels, improving energy, focus, and mood.”
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Did You Know?
- Cortisol peaks 30 minutes after waking up and drops throughout the day.
- It fuels the fight-or-flight response by releasing glucose.
- Chronic high cortisol can weaken bones and suppress immunity.
- Almost every cell in the body has cortisol receptors.
- Stress eating is linked to cortisol, causing cravings for sugary foods.
Top Supplements to Lower Cortisol in 2025
Best for Stress Relief & Mental Clarity: Ashwagandha Extra Strength Formula
Best for Daily Energy & Vitality: Greens Blend
Best for Relaxation & Emotional Balance: Anxiety Shield
Best for Cognitive Support & Mental Clarity: Flawless Bloom CogniUltra
Best for Cortisol Regulation & Sleep Support: Integrative Therapeutics - Cortisol Manager
Best for Cortisol Regulation & Sleep Support: Relacore Extra
01
Best for Stress Relief & Mental Clarity
Ashwagandha Extra Strength Formula
Pros
- Organic and non-GMO
- Includes black pepper for better absorption
- Supports stress relief and cognitive function
- Vegan-friendly
Cons
- May cause mild digestive discomfort
- Not suitable for pregnant or nursing individuals
Form: Capsule | Dosage: 1 capsule twice daily | Servings per container: 60 | Price: $57.60 (30-day supply) | Third-party tested: Yes
Description:
This high-potency adaptogen combines organic ashwagandha root with black pepper extract to enhance absorption. It’s designed to regulate cortisol levels, improve mood, and support overall well-being. Ideal for those seeking natural cortisol reducers and supplements for stress and anxiety.
Things to Consider:
Consult a healthcare provider if you’re on medications or have medical conditions. Consistent use for 60–90 days yields the best results.
In this video, our valued client, Hannah, shares her experience with WOWMD Ashwagandha, explaining how the supplement has helped her manage stress, boost energy, and improve focus for better overall wellness.
Pros
- Combines adaptogens and superfoods
- Supports digestion and detoxification
- Boosts energy and endurance
- Vegan and gluten-free
Cons
- Taste may not appeal to everyone
- May cause mild digestive discomfort initially
Form: Powder | Dosage: 1 scoop (5.4g) daily | Servings per bottle: 28 | Price: $53.10 (1-month supply) | Third-party tested: Yes
Description:
Greens Blend is a nutrient-dense superfood powder that combines organic greens, fruits, and adaptogens like ashwagandha. It’s designed to reduce stress, enhance energy, and support digestion. This blend is ideal for those seeking natural cortisol reducers and overall vitality.
Things to Consider:
Consult a healthcare provider if you’re pregnant, nursing, or on medications. Consistent use for 60–90 days is recommended for optimal results.
In this video, Kelly shares her experience with WOWMD Greens Blend, showcasing how it boosts her energy, supports stress relief, and promotes overall vitality with every sip.
Pros
- Contains adaptogenic herbs like Ashwagandha and Rhodiola
- Promotes relaxation and emotional balance
- Enhances mental clarity and focus
- Vegan and gluten-free
Cons
- May interact with certain medications
- Not suitable for children under 18
Form: Capsule | Dosage: 2 capsules daily | Servings per container: 30 | Price: $55.80 (1-month supply) | Third-party tested: Yes
Description:
Anxiety Shield is a powerful herbal supplement designed to reduce stress and anxiety while supporting mental clarity and emotional balance. With a blend of adaptogens, amino acids, and vitamins, it helps regulate cortisol levels and promotes relaxation naturally.
Things to Consider:
Consult a healthcare provider if you’re on medications or managing a medical condition. Consistent use for 60–90 days is recommended for optimal results.
In this video, Tara shares her experience with WOWMD Anxiety Shield, explaining how the supplement has helped her manage social anxiety, reduce stress, and boost her confidence.
Pros
- Features scientifically-backed ingredients like DMAE and L-Glutamine for optimal brain health
- Enhances focus, clarity, and memory
- Supports mood balance and reduces mental fatigue
- Non-GMO, gluten-free, and no artificial additives
Cons
- May cause mild digestive discomfort in some users
- Not recommended for pregnant or nursing individuals
Form: Capsule | Dosage: 2 Capsule once a day | Servings per container: 30 | Price: $258.88 | Third-party tested: Yes
Description:
CogniUltra is a maximum-strength cognitive formula that combines potent, natural nootropics and brain-boosting nutrients. It’s designed to support neurotransmitter balance, boost memory, and enhance focus. Ideal for those seeking natural mental clarity and improved cognitive function
Things to Consider:
Consult with a healthcare provider if you’re on medications or have existing medical conditions.
05
Best for Cortisol Regulation & Sleep Support
Integrative Therapeutics - Cortisol Manager
Pros
- Contains Sensoril® Ashwagandha for stress reduction
- Promotes restful sleep and relaxation
- Includes L-theanine and Magnolia for cortisol balance
- Gluten-free and vegan-friendly
Cons
- Contains soy (phosphatidylserine)
- May cause drowsiness if taken during the day
Form: Tablet | Dosage: 1 tablet before bedtime (increase to 2 during high stress)| Servings per container: 30 | Price: $25.75 (30 tablets) | Third-party tested: Yes
Description:
Cortisol Manager is a clinically-backed supplement designed to support healthy cortisol levels and promote relaxation. With a blend of adaptogens like Sensoril® Ashwagandha and calming ingredients like L-theanine, it helps manage stress and improve sleep quality.
Things to Consider:
Consult a healthcare provider if pregnant, nursing, or on medications. Best taken in the evening to avoid daytime drowsiness.
Pros
- Targets stress-related belly fat
- Includes vitamins for immune support (Vitamin C, Zinc, B Complex)
- Reduces mild anxiety and stress
- Stimulant-free formula
Cons
- Requires 3 tablets daily
- Not suitable for individuals under 18
Form: Tablet | Dosage: 3 tablets daily | Servings per container: 30 | Price: $29.99 (1-month supply) | Third-party tested: N/A
Description:
Relacore Extra is a stress-mitigating supplement designed to reduce stress-related belly fat while improving mood and energy. Its proprietary blend includes adaptogens like Magnolia and Passionflower, along with essential vitamins and minerals for whole-body balance.
Things to Consider:
Best used alongside a healthy diet and exercise. Consult a healthcare provider if you have medical conditions or are on medications.
Comparison Table
Ashwagandha Extra Strength Formula | Greens Blend | Anxiety Shield | Flawless Bloom CogniUltra | Cortisol Manager | Relacore Extra | |
---|---|---|---|---|---|---|
Third-party tested | Yes | Yes | Yes | Yes | Yes | NA |
Highlights | Organic, includes black pepper for absorption, supports stress relief | Combines adaptogens and superfoods, boosts energy, supports digestion | Adaptogenic herbs, promotes relaxation, enhances mental clarity | Enhances focus, clarity, and memory. | Sensoril® Ashwagandha, promotes restful sleep, balances cortisol | Targets stress-related belly fat, includes immune-supporting vitamins |
Customer Rating | ||||||
Return Policy | 60-day money-back guarantee | 60-day money-back guarantee | 60-day money-back guarantee | 60-day money-back guarantee | NA | Free returns on U.S. orders |
Shipping | Free shipping on orders over $100 | Free shipping on orders over $100 | Free shipping on orders over $100 | Free shipping on all U.S. orders | Expedited shipping available | Free shipping on all U.S. orders |
How Each Supplement Works: Science and Benefits

Cortisol is your body’s internal alarm system, designed to help you respond to stress. However, when this alarm stays on for too long, it can lead to fatigue, anxiety, and even weight gain.
Supplements like ashwagandha, magnesium, and L-theanine work by calming the hypothalamic-pituitary-adrenal (HPA) axis, which regulates cortisol production.
For example, ashwagandha, an adaptogen, has been shown in studies to reduce cortisol levels by up to 33% by helping the body adapt to stress (Ref). Similarly, magnesium supports adrenal health and helps prevent the overactivation of stress responses (Ref).
These supplements also modulate neurotransmitters like GABA and serotonin, which promote relaxation and improve mood. L-theanine, found in green tea, has been shown in a 2021 study to reduce cortisol within hours by calming the nervous system (Ref).
By addressing the root causes of stress, these supplements not only lower cortisol but also enhance overall well-being.
Ready to Feel Calm and Balanced – Try Ashwagandha Extra Strength Today!
How to Use Cortisol Supplements Correctly
Start your day with adaptogens like ashwagandha or Rhodiola rosea, which can be taken in capsule form or added to smoothies for a natural cortisol reducer.
Supplements like magnesium or L-theanine are best taken in the evening to promote relaxation and restful sleep.
Always follow the recommended dosage on the label and pair these supplements with a balanced diet, regular exercise, and mindfulness practices to maximize their benefits. For personalized advice, consult a healthcare provider to ensure these supplements align with your health goals.
Tips for Safer, Faster Results
To get the most from your liquid B12:
- Identify Your Goals: For stress and anxiety, adaptogens like ashwagandha and Rhodiola rosea are excellent natural cortisol reducers. If sleep is your priority, supplements like L-theanine or magnesium can help you unwind while supporting cortisol balance.
- Check the Ingredients: Look for clinically-backed ingredients like Sensoril® Ashwagandha, L-theanine, or Rhodiola. These are among the best supplements to reduce cortisol, with proven benefits in regulating the HPA axis and promoting relaxation. Avoid products with unnecessary fillers or artificial additives.
- Consider Your Lifestyle: If you prefer convenience, capsules or tablets may be the best cortisol supplement for you. For those who enjoy flexibility, powders that can be added to smoothies or teas are a great option. Choose a form that fits seamlessly into your daily routine.
- Look for Third-Party Testing: To ensure safety and efficacy, opt for supplements to reduce cortisol that are third-party tested. This guarantees the product meets quality standards and contains what it claims.
- Consult a Healthcare Professional: Everyone’s body responds differently to supplements. If you’re unsure which natural cortisol reducers are right for you, consult a healthcare provider. They can recommend the best supplement to lower cortisol based on your health history and needs.
ALSO READ: Which Magnesium Is Best For Anxiety and Sleep?
Other Natural Ways to Lower Cortisol

- Exercise Regularly: Activities like yoga, walking, or moderate-intensity workouts help regulate cortisol by promoting relaxation and improving sleep quality.
- Adopt a Balanced Diet: A whole-food, plant-based diet rich in fiber, fruits, and vegetables stabilizes blood sugar and reduces inflammation, both of which are linked to lower cortisol levels.
- Practice Mindfulness: Techniques like meditation, deep breathing, or journaling are powerful natural cortisol reducers. These practices calm the HPA axis, helping you manage stress naturally (Ref).
- Prioritize Sleep: Aim for 7–8 hours of quality sleep each night. A consistent sleep schedule and limiting caffeine can significantly reduce cortisol levels.
ALSO READ: How to Lower Cortisol Levels?
Are Cortisol Supplements Safe?
Cortisol-lowering supplements, including adaptogens like ashwagandha and Rhodiola rosea, are generally considered safe for short-term use when taken as directed.
However, mild side effects such as nausea, drowsiness, or digestive discomfort can occur, and certain supplements may interact with medications or affect conditions like thyroid function.
Long-term safety data are limited, so it’s essential to consult a healthcare provider before starting any regimen, especially if you’re pregnant, nursing, or managing chronic conditions. Choose high-quality, third-party-tested products.
How Long Do Cortisol Supplements Take to Work?
The time it takes for cortisol-lowering supplements to show results can vary depending on the individual and the supplement used.
Adaptogens for cortisol, like ashwagandha and Rhodiola rosea, often begin to reduce stress and cortisol levels within 2 to 4 weeks of consistent use. Supplements and vitamins for stress and anxiety, such as L-theanine or magnesium, may offer quicker, short-term relief, sometimes within hours or days.
For the best results, combine these natural cortisol reducers with lifestyle changes like mindfulness and a balanced diet to manage stress naturally and effectively.
ALSO READ: Adaptogens: Natural Stress Relievers
Real People. Real Results.
Join thousands who trust WOWMD Ashwagandha Extra Strength to manage stress, enhance cognitive function, and improve overall vitality.
I feel more relaxed and focused than ever! Ashwagandha has helped me manage stress and stay calm throughout my busy days. – Kaitlin C., 45-54
I’ve been using it for a month and my energy levels have skyrocketed! It’s the best supplement for reducing stress and improving my mood. – Eric T., 35-44
Try WOWMD Ashwagandha Extra Strength today and feel the difference → Shop Now
Signs Your Cortisol Is Back in Balance
When cortisol levels are balanced, you’ll notice improvements in both physical and mental well-being. Common signs include;
- Steady energy levels throughout the day
- Better sleep quality
- Reduced feelings of stress or anxiety.
Physically, you may experience;
- Stable blood pressure
- Improved digestion
- A stronger immune system
Mentally, balanced cortisol often leads to better focus, emotional stability, and an overall sense of calm. Combining cortisol-lowering supplements, natural cortisol reducers, and lifestyle changes like mindfulness and exercise can help maintain this equilibrium.
Buyers Checklist
- Identify your stress management goals (e.g., better sleep, reduced anxiety).
- Research natural cortisol reducers like adaptogens for cortisol.
- Consult a healthcare provider before starting any supplements.
- Choose third-party-tested, high-quality products.
- Follow recommended dosages on the label.
- Combine supplements with lifestyle changes like mindfulness and exercise.
Conclusion & Final Tips
Managing stress doesn’t have to feel overwhelming. Throughout this guide, we’ve explored how cortisol impacts your body, the role of natural cortisol reducers, and how supplements like adaptogens can restore balance.
By combining the best supplements to reduce cortisol with lifestyle changes like mindfulness and quality sleep, you can regain control over your stress response. You’ll be waking up with calm, clarity, and energy—ready to tackle the day.
The right supplement stack can help you get there. Start small, stay consistent, and take the first step toward a healthier, more balanced you today. You’ve got this!
Transform Your Stress Levels – Try Ashwagandha Extra Strength Shop Now!
Frequently Asked Questions About Cortisol & Supplements
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References
WOWMD follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, qualified experts, and information from top institutions.
- Physiology, cortisol. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK538239/
- Definition of inflammation - NCI Dictionary of Cancer Terms. (n.d.). Cancer.gov. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/inflammation
- Office of Dietary Supplements - Ashwagandha: Is it helpful for stress, anxiety, or sleep? (n.d.). https://ods.od.nih.gov/factsheets/Ashwagandha-HealthProfessional/
- Office of Dietary Supplements - magnesium. (n.d.). https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/
- A randomized, Triple-Blind, Placebo-Controlled, crossover study to investigate the efficacy of a single dose of AlphaWave® L-Theanine on stress in a healthy adult population. https://doi.org/10.1007/s40120-021-00284-x
- Physiology, anterior pituitary. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK499898/
Evidence Based Research
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We follow a strict editorial policy, especially related to the sources we use. Our articles are resourced from reputable online pages, with research drawn from academic institutions and peer-reviewed studies. You can click on the numbers in the parentheses (1, 2, etc.) and check out those references.
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