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Best Mushroom Supplements: Boost Brain & Immunity Naturally
Find the Best Mushroom Supplements in this article, designed to enhance brain focus, immunity, & stress relief. Backed by science. Start your wellness journey today.
By WOWMD Staff
Fact CheckedAdvertiser Disclosure: WOWMD independently vets all recommended products. If you purchase a featured product, we may be compensated. Learn why you can trust us.
Table of contents
Introduction
Mushroom supplements are taking the wellness world by storm, and for good reason. These functional mushrooms, celebrated for centuries in traditional medicine, are now making their way into modern routines as natural powerhouses for health.
From sharpening your mind with mushrooms for brain health, like lion’s mane, to fortifying your immune system with reishi and maitake, the benefits are as diverse as they are compelling. They also boost energy, combat stress, and bring balance to everyday life.
Yet, with popularity comes the need for discernment. Choosing products from the best mushroom supplement brands ensures the quality and potency needed to reap these benefits.
This review covers the top mushroom supplements benefits and how to find the best picks. Read along!
TL;DR
- Mushroom supplements offer targeted benefits like brain health, immunity, and stress relief.
- Lion’s mane, reishi, and chaga are among the best mushrooms for health, each offering unique benefits.
- High-quality supplements prioritize 100% fruiting bodies, organic sourcing, and third-party testing.
- Always consult a healthcare provider for personalized advice before starting.
- WOWMD MyCovital Mushroom Powder is a premium blend designed to enhance vitality, focus, and immunity.
What Are Mushroom Supplements?
Mushroom supplements are a natural powerhouse for health, made from medicinal mushrooms like lion’s mane, reishi, and chaga.
These supplements, available as powders, capsules, and teas, are packed with bioactive compounds such as beta-glucans and antioxidants. And they go way back - we’re talking centuries in traditional medicine.
They’re now backed by modern research for their ability to support immunity, brain health, and overall vitality. Whether it’s boosting focus or managing stress, functional mushrooms offer a holistic approach to wellness.
Why Mushroom Powders Are Gaining Popularity in 2025
Mushroom powders have exploded in popularity in 2025—and for good reason. People are looking for simple, natural ways to boost focus, energy, and immunity without synthetic ingredients or stimulants. Functional mushrooms like lion’s mane, cordyceps, and reishi have been used for centuries, but today’s high-quality powders make it easier than ever to add them to your daily routine—think smoothies, coffee, or capsules.
Whether you're working from home, hitting the gym, or trying to stay sharp as you age, mushroom powders offer real, research-backed benefits that align with modern wellness trends. Plus, they're vegan, adaptogenic, and often third-party tested—making them a smart choice for health-conscious shoppers.
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What Are the Best Mushroom Supplements in 2025?
Picking the right mushroom supplement can feel like a lot with so many choices out there. So, to make it easier for you, we’ve done the heavy lifting. We consulted with experts, did the research, and rounded up the best of the best based on ingredients, effectiveness, and value. Here’s a quick guide to help you find the perfect mushroom supplement for your needs.
Best Overall: WOWMD MyCovital Mushroom Powder
Best for Morning Routine: RYZE Mushroom Coffee
Best Mushroom Blend for Daily Use: Thrive 6
Best for Brain Health: Real Mushrooms Organic Lion’s Mane Powder
Pros
- Contains eight organic mushroom extracts and adaptogenic herbs.
- High-quality, organic ingredients.
- Supports brain health, stress adaptation, and immunity.
- Versatile and easy to incorporate into daily routines.
- Vegan-friendly, non-GMO, and free from artificial additives.
- Convenient powder format for easy mixing.
Cons
- Results may vary.
- Not ideal for those sensitive to adaptogens.
Key Specs
Form: Powder | Dosage: 1 scoop (1.96g) per day | Servings per container: 60 servings | Price: $71.10 | Third-party tested: Yes
Description:
WOWMD MyCovital Mushroom Powder takes the first spot in 2025’s lineup of premium mushroom supplements.
This comprehensive blend of eight organic mushroom extracts, including reishi, lion’s mane, chaga, and cordyceps, is designed to deliver maximum health benefits. Just one scoop daily helps with cognitive clarity, immune resilience, and energy balance.
Things to Consider:
As with most supplements, results can vary. Some people feel the benefits right away, while for others, it might take a little time to kick in. Also, if you’re sensitive to adaptogens, this one might not be the best fit for you.
Our valued client, Cecilia Grizzard, shared an insightful video that highlights the incredible benefits of mushroom supplements. Watch it here to learn more!
WOWMD Mushroom Powder Review: Secret to Better Focus & Gut Support
Pros
- Blends organic coffee with lion’s mane, reishi, cordyceps, and other functional mushrooms.
- Smooth, non-jittery energy suitable for all-day consumption.
- Vegan-friendly and low in caffeine.
- Contains half the caffeine of traditional coffee for balanced energy.
- Free from artificial ingredients, making it a clean and natural choice.
Cons
- May not appeal to those preferring traditional coffee flavors.
- Requires regular use to see noticeable wellness improvements.
Key Specs
Form: Coffee Blend | Dosage: 1 tbsp (6g) daily | Servings per bottle: 30 servings | Price: $27 (1 bag) | Third-party tested: Yes
Description:
This 30-serving blend combines organic coffee with functional mushrooms like lion’s mane, reishi, and cordyceps, offering a unique way to enjoy the benefits of mushrooms. It provides a smooth energy boost, supports mental clarity, enhances immunity, and promotes gut health.
Things to Consider:
If you’re used to the strong, bold flavor of traditional coffee, RYZE Mushroom Coffee’s unique blend might take some getting used to. Also, while it’s great for a steady energy boost, you may need to use it consistently to see noticeable health improvements.
Pros
- Six organic, dual-extracted mushroom fruiting bodies.
- 1,000mg concentrated extract per serving.
- High-quality, pure mushroom extracts.
- Versatile and easy to incorporate into daily routines.
- 100% natural, vegan, non-GMO, and free from fillers or grains.
Cons
- Requires consistent use for noticeable results.
- Earthy flavor may not suit everyone.
Key Specs
Form: Powder | Dosage: 1 scoop (1g) daily | Servings per container: 60 servings | Price: $34.99 (1 tub) | Third-party tested: Yes
Description:
This premium blend features six powerful functional mushrooms—reishi, lion’s mane, chaga, cordyceps, turkey tail, and maitake—designed to support immunity, focus, energy, and overall vitality.
With 1,000mg of concentrated extract per serving (equivalent to 12,000mg of raw mushrooms), it’s a potent and versatile addition to your wellness routine. Each tub comes with 60 servings - 1 scoop daily.
Things to Consider:
To feel the full benefits of Thrive 6, consistency is key. Some users might experience noticeable improvements in energy and focus right away, while others may need a bit more time to see the results.
Pros
- High-quality, pure mushroom extract with verified beta-glucans.
- Free from starch, mycelium, and grain fillers.
- Gluten-free, non-GMO, and vegan-friendly.
- Available in 60g and 150g bulk powder options.
- Versatile powder format for easy use in drinks or recipes.
Cons
- Requires consistent use for noticeable results.
- Slightly higher price point compared to alternatives.
Key Specs
Form: Powder | Dosage: 1 scoop daily | Servings per container: 60 | Price: $34.95 (60g pack) | Third-party tested: Yes
Description:
Real Mushrooms Organic Lion’s Mane Powder is a premium choice for those seeking cognitive and overall wellness support. Made from 100% organic Lion’s Mane mushrooms, this supplement is hot water extracted to ensure maximum potency and bioavailability.
With over 30% beta-glucans guaranteed, it’s a trusted option for enhancing brain function, immune health, and mood. Each pack comes with 60 servings, one serving daily.
Things to Consider:
The key here is consistency. You’ll need to use it regularly to see the full effects, and while it may be a bit more expensive than some other supplements, the quality and purity of the ingredients really make it stand out.
Key Benefits
Top Functional Mushrooms and Their Benefits
- Boosts Brain Health and Cognitive Function: Lion’s mane, often hailed as the best mushroom for brain health, is known for its ability to stimulate nerve growth factors [1]. This can enhance memory, focus, and overall cognitive performance.
- Supports Stress Relief and Emotional Balance: Reishi helps the body adapt to stress, promoting relaxation and better sleep [2].
- Strengthens Immunity: Functional mushrooms like turkey tail and chaga are rich in beta-glucans, which are known to enhance immune system function [3].
- Enhances Energy and Physical Performance: Cordyceps is a favorite among athletes and those looking to boost their energy levels naturally. It helps improve oxygen utilization and stamina, and is often included in the best mushroom powder blends for physical endurance and vitality.
- Provides Antioxidant Protection: Chaga, for instance, is packed with antioxidants that combat oxidative stress and support overall cellular health.
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Dr. Sara Gottfried, board-certified physician and hormone expert:
Mushrooms such as reishi and lion's mane are key adaptogens that help balance the body’s stress response, improve cognitive function, and protect against chronic conditions. They are essential to any holistic health plan.
How to Choose the Right Mushroom Supplement?
How to Choose the Right Mushroom Supplement?
- Understand Your Health Goals: Different functional mushrooms offer unique benefits. Identifying your specific needs will help you choose the best mushroom supplement tailored to your goals.
- Check for Third-Party Testing: Certifications from organizations like NSF or ConsumerLab.com ensure the product is free from contaminants and contains the claimed ingredients.
- Choose the Right Form: Mushroom supplements come in various forms, including powders, capsules, tinctures, and teas. Choose the form that works best for you.
- Check the Source: Opt for supplements made from organically grown mushrooms, preferably sourced from reputable farms.
Unlock the Power of Mushrooms – Shop the Best Mushrooms Supplements Now!
Product Comparison Table
| WOWMD MyCovital Mushroom Powder | RYZE Mushroom Coffee | Thrive 6 Mushroom Extract Powder | Real Mushrooms Organic Lion’s Mane Powder | |
|---|---|---|---|---|
| Key Ingredients | Reishi, Lion’s Mane, Chaga, Cordyceps, and adaptogens | Lion’s Mane, Reishi, Cordyceps, organic coffee | Reishi, Lion’s Mane, Chaga, Cordyceps, Turkey Tail, Maitake | 100% Lion’s Mane mushroom fruiting bodies |
| Primary Benefits | Cognitive clarity, immune support, stress adaptation | Energy boost, focus, gut health | Immunity, focus, energy, overall vitality | Cognitive function, immune health, mood support |
| Format | Powder | Coffee blend | Powder | Powder |
| Customer Rating |  4.9/5 |
 4.5/5 |
 4.3/5 |
 4/5 |
Customer Reviews
“Feeling more energized and focused. Stress levels are down, and I’m powering through the day much better now!” – Brian J. 
“This mushroom powder has given me more energy and improved my mood. I'll be buying it again!” – Kathy R. 
“Using this for a few days now, and I feel more focused and less stressed. I get a steady boost of energy without crashing. It really helps me stay productive throughout the day.” - Sherry 
Mushroom Supplement Checklist for Buyers
- 100% Fruiting Bodies
- Organic Certified
- 3rd Party Tested
- No Fillers or Mycelium
- Transparent Labelling
Did You Know?
- DYK? Mushrooms support gut health and microbiome balance.
- DYK? Turkey Tail may enhance gut immunity.
- DYK? Maitake helps support healthy blood sugar.
- DYK? Cordyceps boosts oxygen absorption and energy.
Final Thoughts
Mushroom supplements are not just a wellness trend; they’re a gateway to better health. From lion’s mane for brain health to reishi for stress relief, these functional mushrooms offer targeted benefits backed by science.
Choosing the right supplement means understanding your goals, prioritizing quality, and selecting trusted brands. Whether you’re seeking energy, immunity, or calm, there’s a mushroom for you.
Ready to elevate your wellness journey? Check out WOWMD MyCovital Mushroom Powder, a premium blend designed to support vitality, focus, and immunity, and also backed by research. Shop Now and Start Seeing Results in Weeks.
Consult your healthcare provider for personalized advice.
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Experience the Benefits of WOWMD Mushroom Powder – Shop Now!
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References
WOWMD follows strict sourcing guidelines to ensure the accuracy of its content, outlined in our editorial policy. We use only trustworthy sources, including peer-reviewed studies, qualified experts, and information from top institutions.
- The Acute and Chronic Effects of Lion’s Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study: https://doi.org/10.3390/nu15224842
- Medicinal Mushrooms: Their Bioactive Components, Nutritional Value and Application in Functional Food Production—A Review: https://doi.org/10.3390/molecules28145393
