Does Berberine Lower Blood Sugar?

Berberine may help lower blood sugar and improve insulin response. Learn what research says about its role in type 2 diabetes and glucose control.

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References

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  1. Efficacy of berberine in patients with type 2 diabetes mellitus: https://pubmed.ncbi.nlm.nih.gov/18442638/
  2. Berberine in the treatment of type 2 diabetes mellitus: a systemic review and meta-analysis: https://pubmed.ncbi.nlm.nih.gov/23118793/
  3. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine: https://pubmed.ncbi.nlm.nih.gov/18397984/
  4. Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action: https://pubmed.ncbi.nlm.nih.gov/18285556/
  5. Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension: https://pubmed.ncbi.nlm.nih.gov/25498346/
  6. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins: https://pubmed.ncbi.nlm.nih.gov/15531889/
  7. Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression: https://pubmed.ncbi.nlm.nih.gov/19800084/
  8. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states: https://pubmed.ncbi.nlm.nih.gov/16873688/